drugset / Trial / NCT06367166
Effects of Bioflavanoids on Vascular Wall Remodeling in Patients With Varicose Veins
Non-randomizedParallel-groupOpen-labelBasic science
Summary
The study is aimed at assessing the dynamics of changes in biochemical markers of venous wall remodeling (type 1 plasminogen activation inhibitor (PAI-1), fibronectin (fibronectin, FN), vimentin (vimentin, VM), von Willebrand factor (vWF), PECAM-1 (CD31) ) in patients with C2s-C3s varicose veins compared with healthy volunteers while taking Venarus® (diosmin in combination with hesperidin).
Timeline
- Start
- 2023-04-01
- Primary completion
- 2026-04-01
- Completion
- 2026-05-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Venarus® | Unknown | 1000 mg | — |