drugset / Trial / NCT06369298

Study of JK07 in Patients With Chronic Heart Failure

NCT06369298 ↗

Phase 2 Active not recruiting 282 enrolled Salubris Biotherapeutics Inc
RandomizedParallel-groupTriple-blindTreatment

Summary

This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart failure. There will be 2 cohorts in this study: Cohort 1: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) of ≤ 40%. Cohort 2: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) \> 40% and ≤ 65%.

Timeline

Start
2024-03-28
Primary completion
2026-10-31
Completion
2026-10-31

Drugs

EvaluationDrugModalityDoseRoute
Comparator JK07 Protein / enzyme biologic — Intravenous