drugset / Trial / NCT06372574

A Study of RO7617991 in Patients With Locally Advanced or Metastatic MAGE-A4-Positive Solid Tumors

NCT06372574

Phase 1 Withdrawn Genentech, Inc.
NaSequentialOpen-labelTreatment

Summary

This study will evaluate the safety, tolerability, and pharmacokinetics of RO7617991, and will make a preliminary assessment of the anti-tumor activity of RO7617991 in human leukocyte antigen (HLA)-A\*02 eligible patients with locally advanced or metastatic melanoma-associated antigen A4 (MAGE-A4)-positive solid tumors.

Timeline

Start
2024-09-30
Primary completion
2028-02-01
Completion
2028-02-01

Drugs

EvaluationDrugModalityDoseRoute
Subject RO7617991 Unknown Intravenous
Background Tocilizumab Monoclonal antibody 8 mg/kg Intravenous

Indications