drugset
drugset / Trial / NCT06372925

Intravascular Imaging Study of the Effect of Inclisiran on Plaque in Patients With Acute Myocardial Infarction

NCT06372925 ↗

Phase 4 Recruiting 318 enrolled Novartis Pharmaceuticals
RandomizedParallel-groupSingle-blindTreatment

Summary

This study is to evaluate the effect of Inclisiran on coronary atherosclerosis using intravascular ultrasound (IVUS) and optical coherence tomography (OCT) in patients with acute myocardial infarction and elevated low-density lipoprotein cholesterol (LDL-C).

Timeline

Start
2024-07-09
Primary completion
2026-12-30
Completion
2027-01-26

Drugs

EvaluationDrugModalityDoseRoute
Subject Inclisiran Small interfering RNA (siRNA) 284 mg Subcutaneous
Background Atorvastatin Small molecule 20 mg Oral

Indications

atherosclerosis