drugset / Trial / NCT06374602

Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer

NCT06374602 ↗

Phase 2 Recruiting 20 enrolled Saint Petersburg State University, Russia
NaSingle-groupOpen-labelTreatment

Summary

This pilot phase 2 study evaluate the effectiveness and safety of pembrolizumab and lenvatinib in patients with anaplastic thyroid cancer. Patients with anaplastic thyroid cancer who are treatment-naive (BRAF-negative) and who were previously treated with chemptherapy or targeted therapy are scheduled to undergo pembrolizumab and lenvatinib and evaluate the outcomes according to the primary and secondary endpoints.

Timeline

Start
2024-03-25
Primary completion
2026-03-25
Completion
2026-06-25

Drugs

EvaluationDrugModalityDoseRoute
Subject Lenvatinib Small molecule 20 mg —
Subject Pembrolizumab Monoclonal antibody 200 mg Intravenous