drugset / Trial / NCT06374602
Efficacy of Pembrolizumab and Lenvatinib in Patients With Anaplastic Thyroid Cancer
NaSingle-groupOpen-labelTreatment
Summary
This pilot phase 2 study evaluate the effectiveness and safety of pembrolizumab and lenvatinib in patients with anaplastic thyroid cancer. Patients with anaplastic thyroid cancer who are treatment-naive (BRAF-negative) and who were previously treated with chemptherapy or targeted therapy are scheduled to undergo pembrolizumab and lenvatinib and evaluate the outcomes according to the primary and secondary endpoints.
Timeline
- Start
- 2024-03-25
- Primary completion
- 2026-03-25
- Completion
- 2026-06-25
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Lenvatinib | Small molecule | 20 mg | — |
| Subject | Pembrolizumab | Monoclonal antibody | 200 mg | Intravenous |