drugset / Trial / NCT06375733

A Study of GFH009 in Combination With Zanubrutinib in Subjects With Relapsed or Refractory DLBCL

NCT06375733

Phase 1/2 Recruiting 51 enrolled Genfleet Therapeutics (Shanghai) Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a multicentre, open-label phase Ib/II study. The purpose of the study is to assess the safety and efficacy of GFH009 in combination with Zanubrutinib in patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL)

Timeline

Start
2024-03-20
Primary completion
2026-12-31
Completion
2026-12-31

Drugs

EvaluationDrugModalityDoseRoute
Subject GFH009 Unknown 60 mg Intravenous
Subject GFH009 Unknown 75 mg Intravenous
Subject GFH009 Unknown 100 mg Intravenous
Subject Zanubrutinib Small molecule 160 mg Oral

Indications