A Phase I Study of [177Lu]Lu-EVS459 in Patients With Ovarian and Lung Cancers

Summary

The purpose of this study is to evaluate the safety, tolerability, dosimetry and preliminary efficacy of \[177Lu\]Lu-EVS459 and the safety and imaging properties of \[68Ga\]Ga-EVS459 in patients aged ≥ 18 years with advanced high-grade serous ovarian cancer (OC) or locally advanced unresectable or metastatic non-squamous non-small cell lung carcinoma (non-sq. NSCLC).

Timeline

Start

2024-09-08

Primary completion

2025-07-10

Completion

2025-07-10

Outcome

Outcome not reported

Stopped (Business): “Study termination based on sponsor decision due to lack of tolerability observed with \[177Lu\]Lu-EVS459”

Drugs

Indications