drugset / Trial / NCT06380647

Comparison of Prophylactic Acyclovir and Placebo in Prevention of Eczema Herpeticum in Pediatric Burns

NCT06380647

Completed 64 enrolled King Edward Medical University
RandomizedParallel-groupSingle-blindPrevention

Summary

Introduction: Early detection is important in treating patients with Eczema Herpeticum (EH), which may arise in paediatric burn patients. As soon as a clinical diagnosis is confirmed, antiviral medications should be started to ensure an early resolution of the disease. Several studies have indicated that acyclovir is the best treatment for EH lesions in the majority of individuals. Objective: Compare efficacy of the prophylactic acyclovir and placebo in preventing eczema Herpeticum in paediatric burn patients

Timeline

Start
2019-10-01
Primary completion
2020-09-30
Completion
2020-09-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Acyclovir Small molecule 5 mg/kg Intravenous
Subject Acyclovir Small molecule 10 mg/kg Intravenous