Tegoprazan-containing Sequential for H. Pylori

Recruiting 400 enrolled Seoul National University Bundang Hospital

RandomizedParallel-groupOpen-labelTreatment

Summary

As H. pylori eradication, the investigators prepared a randomized controlled clinical trial whether tegoprazan-containing 10-day sequential treatment was effective compared to conventional PPI-containing 10-day sequential eradication therapy

Timeline

Start: 2021-02-01
Primary completion: 2026-12-12
Completion: 2026-12-12

Publications

Lee JW, Kim N, Lee J, Jo SY, Lee DH. Efficacy of Tegoprazan-Containing Sequential Eradication Treatment Compared to Esomeprazole-Containing Sequential Eradication of Helicobacter pylori in South Korea, a Region With High Antimicrobial Resistance: A Prospective, Randomized, Single Tertiary Center Study. Helicobacter. 2024 Sep-Oct;29(5):e13143. doi: 10.1111/hel.13143.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Esomeprazole	Small molecule	40 mg	—
Subject	Tegoprazan	Other / unclassified	50 mg	—
Background	Amoxicillin	Other / unclassified	1000 mg	—
Background	Clarithromycin	Small molecule	500 mg	—
Background	Metronidazole	Small molecule	500 mg	—

Tegoprazan-containing Sequential for H. Pylori

Summary

Timeline

Publications

Drugs

Indications