drugset / Trial / NCT06393400

CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC)

NCT06393400

Phase 1 Recruiting 20 enrolled John Lenehan
NaSingle-groupOpen-labelTreatment

Summary

To confirm the safety of combining oral fecal microbiota transplantation (FMT) with gemcitabine and nab-paclitaxel chemotherapy as first line treatment in patients with unresectable or metastatic pancreatic ductal adenocarcinoma.

Timeline

Start
2025-01-08
Primary completion
2028-02
Completion
2028-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Gemcitabine Small molecule 1000 mg/m2 Intravenous
Subject Paclitaxel Small molecule 125 mg/m2 Intravenous
Background polyethylene glycol Other / unclassified 17 g Oral