drugset / Trial / NCT06400251

Testing Ipatasertib as Potentially Targeted Treatment in Cancers With AKT Genetic Changes (MATCH - Subprotocol Z1K)

NCT06400251

Phase 2 Active not recruiting 35 enrolled National Cancer Institute (NCI)
NaSingle-groupOpen-labelTreatment

Summary

This phase II MATCH treatment trial tests how well ipatasertib works in treating patients with cancer that has certain genetic changes called AKT mutations. Ipatasertib is in a class of medications called protein kinase B (AKT) inhibitors. It may stop the growth of cancer cells and may kill them.

Timeline

Start
2019-08-08
Primary completion
2023-06-27
Completion
2027-01-15

Drugs

EvaluationDrugModalityDoseRoute
Subject Ipatasertib Small molecule 400 mg Oral