drugset / Trial / NCT06403761

Investigating How CagriSema, Semaglutide and Cagrilintide Regulate Insulin Effects in the Body of People With Type 2 Diabetes

NCT06403761

Phase 1 Completed 158 enrolled Novo Nordisk A/S
RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will look at how CagriSema, semaglutide and cagrilintide regulate insulin effects in the body of people with type 2 diabetes (T2D). CagriSema is a new investigational medicine that combines two medicines called cagrilintide and semaglutide. Doctors may not yet prescribe CagriSema. Participants will either get CagriSema, semaglutide, cagrilintide, or a ''dummy'' medicine. Which treatment the participants will get is decided by chance. Participants will get the study medicine together with the current daily diabetes medicine metformin. Participants should not take other medicines for diabetes during the study. The study will last for about 42 weeks.

Timeline

Start
2024-05-06
Primary completion
2025-12-28
Completion
2026-02-02

Drugs

EvaluationDrugModalityDoseRoute
Subject Cagrilintide Protein / enzyme biologic Subcutaneous
Subject Semaglutide Peptide Subcutaneous