drugset / Trial / NCT06411860

A Study to Assess the Effect of Olpasiran on QT/QTc Intervals in Healthy Participants

NCT06411860 ↗

Phase 1 Completed 32 enrolled Amgen
RandomizedCrossoverDouble-blindBasic science

Summary

The primary objective of the study is: • To assess the effects of a single therapeutic and supratherapeutic dose of olpasiran on the placebo-corrected change from baseline in QT corrected for heart rate (ΔΔQT)/QTc interval in healthy participants.

Timeline

Start
2024-09-12
Primary completion
2024-11-29
Completion
2024-12-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Moxifloxacin Small molecule — Oral
Subject Olpasiran Unknown — Subcutaneous

Indications

No indication recorded.