Ciprofol Versus Propofol in Patients Undergoing Painless Hysteroscopy

Not yet recruiting 188 enrolled Baoding First Central Hospital

RandomizedParallel-groupDouble-blindTreatment

Summary

Ciprofol exhibits comparable efficacy to that of propofol, and is associated with less injection pain rate, fewer adverse events, higher patient satisfaction, and more stable hemodynamics when used for general anesthesia during the painless hysteroscopy.

Timeline

Start: 2024-08-10
Primary completion: 2024-09-09
Completion: 2024-09-10

Outcome

Met primary endpoint

paper The injection pain rate of ciprofol group (18.35%) was significantly lower than the propofol group (40.74%). PMID 39533194 ↗

Publications

Li A, Li N, Zhu L, Xu Z, Wang Y, Li J, Zhang G. The efficacy and safety of ciprofol versus propofol in patients undergoing painless hysteroscopy: a randomized, double-blind, controlled trial. BMC Anesthesiol. 2024 Nov 12;24(1):411. doi: 10.1186/s12871-024-02787-0.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Cipepofol	Small molecule	0.4 mg/kg	—
Comparator	Propofol	Small molecule	2 mg/kg	—

Indications

No indication recorded.