drugset / Trial / NCT06414434

BTX-A51 in Patients With Liposarcoma or CIC-rearranged Sarcoma

NCT06414434 ↗

Phase 1 Active not recruiting 24 enrolled Michael Wagner, MD Edgewood Oncology Inc. · collab
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This study is testing two different doses of BTX-A51 to determine if it is safe and tolerable in participants with liposarcoma with MDM2 amplification, myxoid liposarcoma, and CIC-rearranged sarcoma. The name of the study drug used in this research study is: -BTX-A51 (a type of kinase inhibitor)

Timeline

Start
2024-09-30
Primary completion
2027-01-15
Completion
2027-06-01

Drugs

EvaluationDrugModalityDoseRoute
Subject BTX-A51 Small molecule 21 mg Oral
Subject BTX-A51 Small molecule 30 mg Oral