drugset / Trial / NCT06414460

Study of ISM3412 in Participants With Locally Advanced/Metastatic Solid Tumors

NCT06414460 ↗

Phase 1/2 Recruiting 114 enrolled InSilico Medicine
Non-randomizedSequentialOpen-labelTreatment

Summary

The study has consists of two parts, a dose escalation part (Part 1) and a dose selection optimization part (Part 2). The primary objectives of this study are to evaluate the safety and tolerability of ISM3412 in participants with locally advanced/metastatic solid tumors, and to determine the RP2D of ISM3412.

Timeline

Start
2025-04-25
Primary completion
2028-03-31
Completion
2029-03-31

Drugs

EvaluationDrugModalityDoseRoute
Subject ISM3412 Unknown — Oral