A Study to Evaluate the Impact of Clascoterone 1% Cream on Skin Barrier Properties in Acne Prone Patients

Summary

Acne medications are a common source of facial dryness resulting in skin barrier damage and poor patient compliance. Retinoids and benzoyl peroxide are some of the most frequently prescribed and effective acne medications, however, dryness is an unwanted side effect. A new acne medication, 1% clascoterone, has been placed in a novel vehicle for excellent drug delivery in combination with excellent barrier properties. The barrier properties of 1% clascoterone have never been demonstrated. This study is aimed at better understanding the positive barrier effects of 1% clascoterone.

Timeline

Start

2023-11-27

Primary completion

2023-12-16

Completion

2023-12-16

Outcome

Missed primary endpoint

registry Winlevi (Clascoterone) 1% Un-treated Side (UT); p <0.001; t-test, 2 sided NCT06415292 ↗

Drugs

Indications