drugset / Trial / NCT06417320
Effect of Sodium-glucose Cotransporter-2 Inhibitors (SGLT-2i) on Proteinuria in Nephrotic Children Older Than 10 Years
RandomizedParallel-groupDouble-blindTreatment
Summary
The goal of this clinical trial is to evaluate the effect of ACE inhibitors and SGLT-2 inhibitors on: 1. Proteinuria 2. Renal survival indices
Timeline
- Start
- 2023-06-01
- Primary completion
- 2025-01
- Completion
- 2025-08
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Captopril | Small molecule | 0.2 mg/kg | Oral |
| Comparator | Captopril | Small molecule | 0.6 mg/kg | Oral |
| Comparator | Forxiga | Unknown | 5 mg | — |
| Comparator | Forxiga | Unknown | 10 mg | — |