drugset / Trial / NCT06419673

Serplulimab Plus Chemoradiotherapy for Stage III-IVA Cervical Cancer

NCT06419673

Phase 2 Active not recruiting 240 enrolled Cancer Institute and Hospital, Chinese Academy of Medical Sciences
RandomizedParallel-groupSingle-blindTreatment

Summary

This study is a prospective, multicenter, randomized, open controlled clinical trial aimed at evaluating the effectiveness and safety of serplulimab plus chemoradiotherapy in FIGO 2018 stage III or IVA cervical squamous cell carcinoma, adenocarcinoma, and adenosquamous cell carcinoma patients who have not received prior treatment.

Timeline

Start
2024-05-01
Primary completion
2025-05-31
Completion
2028-05-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Serplulimab Monoclonal antibody 300 mg Intravenous
Background Carboplatin Small molecule Intravenous
Background Cisplatin Other / unclassified 40 mg/m2 Intravenous

Indications