drugset / Trial / NCT06420063

Sequential CAR-T Cells Targeting CD33/CD123 in Patients With Acute Myelocytic Leukemia AML

NCT06420063 ↗

Phase 1/2 Recruiting 85 enrolled Essen Biotech
NaSingle-groupOpen-labelTreatment

Summary

This is an open, single-arm, clinical study to evaluate the efficacy and safety of chimeric antigen receptor T cell immunotherapy (CAR-T) targeting CD33 or CD123 or both sequentially in the treatment of Acute Myelocytic Leukemia.

Timeline

Start
2024-07-10
Primary completion
2025-12-10
Completion
2026-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject CD123/CD33 CART Cell therapy — Intravenous