drugset
drugset / Trial / NCT06424756

Effects of an Antioxidant Supplement on Blood Vessel Health

NCT06424756 ↗

Phase 2 Recruiting 60 enrolled University of Georgia
RandomizedCrossoverTriple-blindTreatment

Summary

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and the non-Hispanic Black (NHB) population is disproportionately affected. Our research has previously demonstrated that oxidative stress may contribute to reduced vascular function in otherwise healthy NHB adults, potentially predisposing them to the development of hypertension and CVD. This study is designed to examine whether the mitochondria are an important source of oxidative stress-induced vascular dysfunction in healthy NHB adults.

Timeline

Start
2024-07-01
Primary completion
2030-03-31
Completion
2030-03-31

Drugs

EvaluationDrugModalityDoseRoute
Background L-NAME Unknown — Other
Background MitoTempo Unknown — Other
Background Sodium Nitroprusside Unknown — Other
Background Tempol Small molecule — Other

Indications

No indication recorded.