drugset / Trial / NCT06424821

Cadonilimab Plus Chemotherapy as First-line Treatment for PD-L1 Negative NSCLC

NCT06424821 ↗

Phase 2 Unknown 54 enrolled Shanghai Pulmonary Hospital, Shanghai, China
NaSingle-groupOpen-labelTreatment

Summary

The goal of this clinical trial is to investigate the efficacy, safety and tolerability of PD-1/CTLA-4 inhibitor (Cadonilimab) combination with chemotherapy as first-line treatment for PD-L1 negative advanced non small cell lung cancer patients. And also explore the potential biomarkers for predicting the efficacy of PD-1/CTLA-4 inhibitor for advanced non small cell lung cancer.

Timeline

Start
2023-07-04
Primary completion
2024-09-04
Completion
2025-09-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 10 mg/kg Intravenous