Post Extraction Changes Following Ridge Preservation Using Partially Demineralized Dentin Block Versus Xenograft

Summary

The aim of this study is to clinically and radiographically evaluate the dimensional changes of hard tissue after using Partially Demineralized Dentin Block versus Xenograft in the esthetic zone. The main question: In patients with unrestorable teeth, will the use of partially demineralized Dentin Block be more effective than Xenograft in preserving vertical and horizontal ridge dimensions? After enrollment, a thorough preoperative assessment, including history taking, clinical, and radiographic examinations, will be conducted. Initial therapy includes periodontal treatment (phase 1 therapy) followed by random assignment to one of two treatment groups: ridge preservation using Partially Demineralized Dentin Block or Xenograft. Both groups will undergo atraumatic extraction. For the test group, an autogenous partially demineralized dentin graft will be prepared, involving tooth cleaning, grinding, and partial demineralization with the Tooth Transformer device, followed by Leukocyte-Platelet Rich Fibrin (L-PRF) membrane and liquid fibrinogen preparation. The L-PRF membranes will be cut, mixed with dentin particles, and combined with liquid fibrinogen to form a compact graft. The block will be placed inside the socket and covered by an L-PRF membrane and secured with a cross-suture. In the control group, Xenograft will be used, and the socket filled with deproteinized bovine bone mineral, covered with a collagen membrane, and secured with a cross-suture. After a healing period of 6 months, at the time of implant placement, a biopsy will be taken using a trephine bur.

Timeline

Start

2024-03-01

Primary completion

2025-07-30

Completion

2025-07-30

Drugs

Indications

No indication recorded.