Behavioural Activation Therapy and Esketamine for Resistant Depression

Summary

This is a randomized clinical trial to test the effectiveness of combining a proven psychological intervention called behavioural activation therapy alongside esketamine treatment for treatment resistant major depressive episodes in individuals with major depressive disorder or bipolar disorder. Encouraging participants to practice new behaviours while their mood is improved through esketamine treatment may lead to more lasting recovery from depression.

Timeline

Start

2024-06-11

Primary completion

2025-09-17

Completion

2025-09-17

Drugs

Indications