drugset / Trial / NCT06438822

Cadonilimab Combined With Liposomal Irinotecan Plus Leucovorin and Fluorouracil for Advanced Cholangiocarcinoma

NCT06438822 ↗

Phase 2 Recruiting 51 enrolled West China Hospital
NaSingle-groupOpen-labelTreatment

Summary

This study aimed to evaluate the efficacy and safety of the combination of cadonilimab with liposomal irinotecan plus fluorouracil and leucovorin for the treatment of advanced biliary tract cancer.

Timeline

Start
2024-08-30
Primary completion
2026-08-30
Completion
2026-11-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Cadonilimab Monoclonal antibody 6 mg/kg —
Subject Irinotecan Small molecule 70 mg/m2 Intravenous
Subject Leucovorin Small molecule 400 mg/m2 —
Subject fluorouracil Small molecule 2400 mg/m2 —

Indications