drugset / Trial / NCT06444399

Deucravacitinib (BMS-986165) for Pityriasis Rubra Pilaris

NCT06444399

Phase 2 Completed 7 enrolled Mayo Clinic
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to evaluate the safety and effectiveness of Deucravacitinib (BMS-986165) in Pityriasis Rubra Pilaris as assessed by the change in Investigator Global Assessment (IGA), PASI- 50, 75, 90, DLQI, NRS itch, and Skindex-16 at week 24. To predict responses through the identification of unique biomarkers of PRP utilizing single-cell RNA sequencing.

Timeline

Start
2024-07-29
Primary completion
2025-09-02
Completion
2026-05-01

Drugs

EvaluationDrugModalityDoseRoute
Subject CRAVACITINIB Small molecule 6 mg Oral