Effects of THC on Alcohol Consumption and Neural Correlates of Reward

Summary

Alcohol and cannabis are often used together such that their effects overlap, but little is known about the neural mechanisms that underlie simultaneous use. High doses of THC have not been well-studied in the laboratory, and it is unclear how high doses of THC may impact alcohol consumption patterns. The proposed study will explore the effects of oral THC (20mg dronabinol) vs. placebo on neural reward, alcohol self-administration and naturalistic co-use patterns.

Timeline

Start

2024-07-01

Primary completion

2026-06-30

Completion

2026-06-30

Drugs

Indications