Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness

Summary

This study is a trial looking at a drug to help prevent acute mountain sickness. The drug is prochlorperazine, a drug commonly used to treat nausea vomiting and headache. Participants will either take the drug or a placebo, and hike to and sleep at the summit of Mount Blue Sky located at 4,348 meters (14,265 feet).

Timeline

Start

2024-08-05

Primary completion

2024-08-28

Completion

2024-08-28

Publications

• Small E, Goldberg E, Musi M, Strickland B, Paterson R, Phillips C, Keyes LE. Prochlorperazine maleate versus placebo for the prevention of acute mountain sickness: study protocol for a randomized controlled trial. Trials. 2024 Nov 21;25(1):785. doi: 10.1186/s13063-024-08592-x.

Drugs

Indications