Effects of Antiemetic Agents in Orthognathic Surgery Patients

Summary

In an effort to prevent or treat consistently high rates of PONV following maxillofacial operations, several medications, techniques and multimodal protocols have been studied. In the present study, the investigators hypothesized that combining metoclopramide with granisetron will improve PONV incidence when compared with granisetrone alone.

Timeline

Start

2020-04-14

Primary completion

2021-04-05

Completion

2021-04-05

Publications

• Doganay Ozyilmaz O, Bayburt KA, Alkan A, Uysal H. Effects of Combined Antiemetic Protocol for the Prevention of Postoperative Nausea and Vomiting in Orthognathic Surgery: A Randomized Double Blinded Clinical Study. J Oral Maxillofac Surg. 2025 Apr;83(4):429-438. doi: 10.1016/j.joms.2024.12.010. Epub 2024 Dec 27.

Drugs

Indications