drugset / Trial / NCT06458595

Safety and Tolerability of KH658 Gene Therapy in Subjects With Neovascular Age-related Macular Degeneration (nAMD)

NCT06458595 ↗

Phase 1/2 Recruiting 44 enrolled Chengdu Origen Biotechnology Co., Ltd.
NaSequentialOpen-labelTreatment

Summary

KH658 is a adeno-associated virus (AAV) vector-based gene therapy for suprachoroidal space injection. The long-term, stable therapeutic protein after one time injection for nAMD could potentially reduce the treatment burden and maintain vision.

Timeline

Start
2024-06-28
Primary completion
2026-03-31
Completion
2026-12-28

Drugs

EvaluationDrugModalityDoseRoute
Subject KH658 Gene therapy (AAV / viral vector) — Other