drugset / Trial / NCT06466655
Daily Stress and Vascular Function in Midlife as a Risk Factor for Cognitive Decline
Completed
17 enrolled
University of Delaware
National Institute of General Medical Sciences (NIGMS) · collab
Non-randomizedSingle-groupOpen-labelBasic science
Summary
The goal of this pilot clinical trial is to begin to understand how day-to-day stress affects cardiovascular health and brain function in middle-aged adults. The main question aims to answer is whether the link between daily stress and vascular dysfunction is a potential mechanism of increased risk for future cognitive decline. Participants will complete a 15-day testing cycle. During this cycle, participants will complete daily assessments of stress using an online survey tool for 14-consecutive days. On the last day of each cycle, vascular function will be assessed during a laboratory visit.
Timeline
- Start
- 2024-05-30
- Primary completion
- 2025-04-10
- Completion
- 2025-05-29
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | MitoTempol | Unknown | 0.5 mmol | Other |