drugset / Trial / NCT06471959

Psychedelic-assisted Group Program for First Responders

NCT06471959

NaSequentialOpen-labelTreatment

Summary

This study is a two-group feasibility study of oral psilocybin combined with a 12-week group-based program, customized for firefighters. Trained facilitators will help create a trauma-informed space for the group (n = 6-8) to thrive and promote cognitive resilience. The topics covered throughout the 12 weeks include breath-work, mindfulness, self-compassion, embodiment, and Internal Family Systems work. Group 1 (control): 12-week group-based program, with a breathwork day at week 10 Group 2 (intervention): 12-week group-based program, with a 10mg dose of psilocybin (PEX010) at Week 10 Assessment timepoints: * Baseline * Mid-program (Week 6) * End of program (Week 12) * 6-month follow up

Timeline

Start
2025-01-01
Primary completion
2025-07-01
Completion
2025-09-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Psilocybin Other / unclassified 10 mg Oral

Indications

No indication recorded.