drugset / Trial / NCT06474078

Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN

NCT06474078

Completed 20 enrolled Chang Gung Memorial Hospital
NaSingle-groupOpen-labelTreatment

Summary

The goal of this study is to evaluate the effect of tofacitinib in patients with Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). The primary outcome of the study is the time to complete re-epithelialization. The secondary outcomes are to determine mortality, length of hospitalization, adverse events, the time to beginning of epithelization, the time to halting of progression of SJS/TEN, ocular complications, and infections.

Timeline

Start
2022-08-01
Primary completion
2025-06-20
Completion
2025-06-20

Drugs

EvaluationDrugModalityDoseRoute
Subject Tofacitinib Small molecule 5 mg Oral
Subject Tofacitinib Small molecule 10 mg Oral