drugset / Trial / NCT06474078
Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TEN
NaSingle-groupOpen-labelTreatment
Summary
The goal of this study is to evaluate the effect of tofacitinib in patients with Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN). The primary outcome of the study is the time to complete re-epithelialization. The secondary outcomes are to determine mortality, length of hospitalization, adverse events, the time to beginning of epithelization, the time to halting of progression of SJS/TEN, ocular complications, and infections.
Timeline
- Start
- 2022-08-01
- Primary completion
- 2025-06-20
- Completion
- 2025-06-20
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Tofacitinib | Small molecule | 5 mg | Oral |
| Subject | Tofacitinib | Small molecule | 10 mg | Oral |