drugset / Trial / NCT06482294
CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma
RandomizedCrossoverOpen-labelTreatment
Summary
Single-center, interventional, open-label, randomized phase II study aimed at describing the changes in airway inflammation at the onset of asthma symptoms that lead to the use of rapid acting bronchodilator (RABD) as a rescue medication in a mild to moderate asthma population. The study will assess whether there are differences in the airway inflammation profile in patients using a reliever medication containing ICS (anti-inflammatory rescue strategy) compared to a reliever medication containing only a bronchodilator for symptom relief (Non anti-inflammatory rescue strategy).
Timeline
- Start
- 2024-06-18
- Primary completion
- 2025-05-01
- Completion
- 2025-07-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Beclomethasone | Small molecule | 400 ug | Inhaled |
| Subject | Budesonide | Small molecule | 200 ug | Inhaled |
| Subject | Budesonide | Small molecule | 400 ug | Inhaled |
| Subject | Fluticason | Other / unclassified | 250 ug | Inhaled |
| Background | Salbutamol | Unknown | 200 ug | Inhaled |