drugset / Trial / NCT06482294

CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma

NCT06482294

Phase 2 Unknown 80 enrolled Università degli Studi di Ferrara
RandomizedCrossoverOpen-labelTreatment

Summary

Single-center, interventional, open-label, randomized phase II study aimed at describing the changes in airway inflammation at the onset of asthma symptoms that lead to the use of rapid acting bronchodilator (RABD) as a rescue medication in a mild to moderate asthma population. The study will assess whether there are differences in the airway inflammation profile in patients using a reliever medication containing ICS (anti-inflammatory rescue strategy) compared to a reliever medication containing only a bronchodilator for symptom relief (Non anti-inflammatory rescue strategy).

Timeline

Start
2024-06-18
Primary completion
2025-05-01
Completion
2025-07-01

Drugs

EvaluationDrugModalityDoseRoute
Subject Beclomethasone Small molecule 400 ug Inhaled
Subject Budesonide Small molecule 200 ug Inhaled
Subject Budesonide Small molecule 400 ug Inhaled
Subject Fluticason Other / unclassified 250 ug Inhaled
Background Salbutamol Unknown 200 ug Inhaled

Indications