drugset / Trial / NCT06486025
Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia
RandomizedParallel-groupOpen-labelTreatment
Summary
There is still no evidence of the appropriate dose to be used. Serum magnesium sulfate concentration is not measured regularly, thus we may be using sub-therapeutic level or reaching a toxic level.Overweight and obese women have different pharmacokinetics and different drug distribution, therefore, they may need higher doses of magnesium sulfate to reach therapeutic level.
Timeline
- Start
- 2024-07-01
- Primary completion
- 2024-09-15
- Completion
- 2024-10-01
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Magnesium Sulfate | Other / unclassified | 1 g | — |
| Comparator | Magnesium Sulfate | Other / unclassified | 2 g | — |