drugset / Trial / NCT06486025

Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia

NCT06486025

Phase 1/2 Unknown 100 enrolled Ain Shams University
RandomizedParallel-groupOpen-labelTreatment

Summary

There is still no evidence of the appropriate dose to be used. Serum magnesium sulfate concentration is not measured regularly, thus we may be using sub-therapeutic level or reaching a toxic level.Overweight and obese women have different pharmacokinetics and different drug distribution, therefore, they may need higher doses of magnesium sulfate to reach therapeutic level.

Timeline

Start
2024-07-01
Primary completion
2024-09-15
Completion
2024-10-01

Drugs

EvaluationDrugModalityDoseRoute
Comparator Magnesium Sulfate Other / unclassified 1 g
Comparator Magnesium Sulfate Other / unclassified 2 g

Indications