drugset / Trial / NCT06487221

Avutometinib and Defactinib in Diffuse Gastric Cancer

NCT06487221

Phase 2 Recruiting 27 enrolled Ryan H. Moy, MD, PhD Verastem, Inc. · collab
NaSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to determine if the combination study treatment with avutometinib and defactinib will prolong life in participants, is effective in decreasing the size of the tumor(s), and if it is safe in subjects with diffuse-type stomach cancer.

Timeline

Start
2024-10-28
Primary completion
2028-11-30
Completion
2029-05-30

Drugs

EvaluationDrugModalityDoseRoute
Subject Avutometinib Small molecule 3.2 mg Oral
Subject Defactinib Small molecule 200 mg Oral