drugset / Trial / NCT06494891
Motivation for IV Alcohol Self-Administration in Humans
Phase 2
Recruiting
210 enrolled
University of California, Los Angeles
National Institute on Alcohol Abuse and Alcoholism (NIAAA) · collab
NaSingle-groupOpen-labelOther
Summary
The goal of this translational study is to understand different reasons why people between the ages of 21 and 65 with alcohol use disorder are motivated to self-administer alcohol. The main questions it aims to answer are: * How does a person's desire for a reward affect their motivation to self-administer alcohol? * How does a person's emotions affect their motivation to self-administer alcohol? * How does a person's cognitive functioning affect their motivation to self-administer alcohol? Participants will be asked to complete questionnaires about their mood, habits, and functioning and will complete an IV alcohol administration that will include pressing a button to receive additional doses of IV alcohol.
Timeline
- Start
- 2024-01-16
- Primary completion
- 2027-04-30
- Completion
- 2027-06-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Alcohol | Other / unclassified | — | Intravenous |