drugset / Trial / NCT06495307
RHPRG4 FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD)
NaSingle-groupOpen-labelTreatment
Summary
rhPRG4-GVHD-001 is a prospective multi-center study conducted in Australia to evaluate the safety and efficacy of topically-applied rhPRG4 in subjects with moderate to severe dry eye secondary to chronic GVHD.
Timeline
- Start
- 2025-02-14
- Primary completion
- 2025-03-22
- Completion
- 2025-03-22
Outcome
Outcome not reported
Stopped: “Efficacy signal substantial enough to more to larger study”
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | rhPRG4 | Protein / enzyme biologic | 450 ug/ml | Topical |