drugset / Trial / NCT06496750
Ketamine for Methamphetamine Use Disorder
RandomizedParallel-groupTriple-blindTreatment
Summary
This study aims to determine whether treatment response with IV ketamine is superior to treatment response with IV midazolam in adults with moderate to severe MUD. The study design is a 12-week randomized, double-blind, controlled trial comparing intravenous (IV) ketamine against IV midazolam, delivered over six weeks in 120 adults with moderate to severe methamphetamine use disorder (MUD).
Timeline
- Start
- 2024-09-11
- Primary completion
- 2026-08-18
- Completion
- 2026-10-15
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ketamine | Small molecule | 0.5 mg/kg | Intravenous |
| Comparator | Midazolam | Small molecule | 0.02 mg/kg | Intravenous |