drugset / Trial / NCT06499090

Mirtazapine for Acute and Chronic Post Mastectomy Pain

NCT06499090

Phase 0 Completed 62 enrolled Assiut University
RandomizedParallel-groupDouble-blindPrevention

Summary

Our aim in this study will be to investigate the effect of mirtazapine on acute post-mastectomy pain manifested by total morphine consumption in first 24 hours and VAS score at rest and movement (primary outcomes). chronic neuropathic pain using LANSS Pain Scale (Leeds Assessment of Neuropathic Signs and Symptoms) and to evaluate the quality of recovery using the quality of recovery-40scoring system(QoR-40) (secondary outcomes) following modified radical mastectomy for breast cancer.

Timeline

Start
2024-03-01
Primary completion
2025-12-10
Completion
2025-12-20

Drugs

EvaluationDrugModalityDoseRoute
Comparator Mirtazapine Other / unclassified 30 mg Oral

Indications