Powdered Intrawound Vancomycin in Open Fractures Trial

Summary

The purpose of this randomized control trial is to compare the rate of post-operative infection in patients with open fractures in upper or lower extremity long bones randomized to receive intra-operative intrawound topical vancomycin powder on their open fractures in addition to the current best practice of intravenous antibiotics with irrigation and debridement compared to intravenous antibiotics with irrigation and debridement alone during definitive operative fixation of the fracture.

Timeline

Start

2024-11-01

Primary completion

2028-09-01

Completion

2029-09-01

Drugs

Indications