drugset / Trial / NCT06505135

Stem Cell Treatment for Regeneration of the Rotator Cuff (Lipo-Cuff Study)

NCT06505135

Phase 1 Enrolling by invitation 30 enrolled University of Southern Denmark
RandomizedParallel-groupOpen-labelTreatment

Summary

Treatment of rotator cuff tears with micro-fragmented adipose tissue is a minimal-invasive procedure with the potential to shorten and ease recovery, accelerate return to daily activity and work of thus with a potential capacity to improve the functional result compared to conventional surgery alone. The study will provide evidence whether the addition of micro-fragmented adipose tissue therapy can augment conventional rotator cuff tear treatment. The study will also reveal whether this treatment can be feasible for standard care of patients with rotator cuff tear as it will be simple to standardize. Moreover, besides providing a novel treatment for patients with rotator cuff tears, the project will based on data from muscle biopsies and scanning modalities, generate new knowledge, preparing for precision regenerative medicine in shoulder disease.

Timeline

Start
2024-09-03
Primary completion
2026-09
Completion
2026-09

Drugs

EvaluationDrugModalityDoseRoute
Subject Micro Fragmented Adipose Tissue Cell therapy 10 ml Intramuscular

Indications