A 20-Week Study Assessing the Efficacy of Apremilast in Patients with EB Simplex Generalized

Summary

The goal of this clinical trial is to Assessing the Efficacy and Safety of Apremilast in Patients \> 6 years of age with EB simplex generalized . The main question it aims to answer are: describe efficacity of this treatment. Participants will take treatments and have to use bullets during the study period.

Timeline

Start

2024-08-06

Primary completion

2025-10-01

Completion

2026-04-01

Publications

• Fontas E, Hubiche T, Maruani A, Moschoi R, Hussain S, Chiaverini C. Multicentre phase II open study assessing the efficacy and safety of apremilast in children and adults with epidermolysis bullosa simplex generalised: study protocol for the EBULO study. BMJ Open. 2025 Nov 12;15(11):e103194. doi: 10.1136/bmjopen-2025-103194.

Drugs

Indications