drugset / Trial / NCT06518291

COMPARISON OF NITROFURANTOIN WITH FOSFOMYCIN in TREATING CYSTITIS IN WOMEN

NCT06518291

Phase 4 Not yet recruiting 392 enrolled Shalamar Institute of Health Sciences
RandomizedParallel-groupOpen-labelTreatment

Summary

Fosfomycin and nitrofurantoin are increasingly being prescribed in outpatients for the oral treatment of urinary tract infection (UTI). The newest guidelines for empirical treatment of women with uncomplicated urinary tract infections (UTIs) advise clinicians to choose among three venerable antibiotics: trimethoprim-sulfamethoxazole, nitrofurantoin, and fosfomycin. Although both nitrofurantoin and fosfomycin have shown efficacy against most urinary pathogens, no recent head-to-head comparisons have been reported. So, this study will be conducted to compare effectiveness of both drugs.

Timeline

Start
2025-01
Primary completion
2025-06
Completion
2025-06

Drugs

EvaluationDrugModalityDoseRoute
Comparator Fosfomycin Small molecule 3 g Oral
Comparator Nitrofurantoin Unknown 100 mg Oral