drugset / Trial / NCT06518850
Study of Clinical Features and Efficacy of Small Intestinal Bacterial Overgrowth in Patients With Abdominal Distension
Phase 1/2
Not yet recruiting
30 enrolled
Peking Union Medical College Hospital
Air Force Military Medical University, China · collabBeijing Aerospace General Hospital · collabBeijing Chao Yang Hospital · collabBeijing Friendship Hospital · collabBeijing Jishuitan Hospital · collabBeijing Tiantan Hospital · collabBeijing Tongren Hospital · collabChina-Japan Friendship Hospital · collabNavy General Hospital, Beijing · collabPeking University Third Hospital · collabThe Luhe Teaching Hospital of the Capital Medical University · collab
Non-randomizedParallel-groupOpen-labelOther
Summary
Most studies of bloating have focused on functional factors, while data on organic abdominal distention are rare, and studies that combine small intestine bacterial overgrowth and/or oral cecum transit time abnormalities are more urgent to explore. On this basis, patients with functional abdominal distension complicated with small intestine bacterial overgrowth were divided according to whether there was abnormal oral cecum transit time, and given the same treatment plan. The relief effect of abdominal distension, small intestine bacterial overgrowth turning negative and oral cecum transit time recovery were observed, so as to further clarify the cause of abdominal distension patients.
Timeline
- Start
- 2024-08-01
- Primary completion
- 2024-12-31
- Completion
- 2025-12-31
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Rifaximin | Other / unclassified | 0.2 g | — |