drugset / Trial / NCT06519344
An Exploratory Clinical Study Evaluating the Safety and Efficacy of Intravenous Anti-CD20/CD30-CAR-T Cell Infusion in Relapsed/Refractory Lymphoma Patients.
Phase 0
Not yet recruiting
12 enrolled
Shanghai Tongji Hospital, Tongji University School of Medicine
NaSingle-groupOpen-labelTreatment
Summary
This study is a single-center,open-label,single-dose clinical trial of anti-CD20/CD30-CAR-T cell therapy in relapsed/refractory B-cell tumor patients after lymphocyte depletion pre-treatment. In this study phase,a traditional "3+3"trial design is employed for dose escalation.
Timeline
- Start
- 2024-07-31
- Primary completion
- 2026-07-30
- Completion
- 2027-07-30
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | anti-CD20/CD30-CAR-T Cells | Cell therapy | 300000 cells/kg | Intravenous |
| Subject | anti-CD20/CD30-CAR-T Cells | Cell therapy | 1e+06 cells/kg | Intravenous |
| Subject | anti-CD20/CD30-CAR-T Cells | Cell therapy | 3e+06 cells/kg | Intravenous |