drugset / Trial / NCT06519344

An Exploratory Clinical Study Evaluating the Safety and Efficacy of Intravenous Anti-CD20/CD30-CAR-T Cell Infusion in Relapsed/Refractory Lymphoma Patients.

NCT06519344 ↗

NaSingle-groupOpen-labelTreatment

Summary

This study is a single-center,open-label,single-dose clinical trial of anti-CD20/CD30-CAR-T cell therapy in relapsed/refractory B-cell tumor patients after lymphocyte depletion pre-treatment. In this study phase,a traditional "3+3"trial design is employed for dose escalation.

Timeline

Start
2024-07-31
Primary completion
2026-07-30
Completion
2027-07-30

Drugs

EvaluationDrugModalityDoseRoute
Subject anti-CD20/CD30-CAR-T Cells Cell therapy 300000 cells/kg Intravenous
Subject anti-CD20/CD30-CAR-T Cells Cell therapy 1e+06 cells/kg Intravenous
Subject anti-CD20/CD30-CAR-T Cells Cell therapy 3e+06 cells/kg Intravenous

Indications