drugset / Trial / NCT06522737

A Study of Duvelisib Versus Gemcitabine or Bendamustine in Participants With Relapsed/Refractory Nodal T Cell Lymphoma With T Follicular Helper (TFH) Phenotype

NCT06522737

Phase 3 Recruiting 124 enrolled SecuraBio
RandomizedParallel-groupOpen-labelTreatment

Summary

The study will evaluate the progression-free survival benefit of duvelisib monotherapy as compared to investigator's choice of gemcitabine or bendamustine in participants with relapsed/refractory nodal T cell lymphoma with TFH phenotype.

Timeline

Start
2025-05-19
Primary completion
2028-02
Completion
2028-12

Drugs

EvaluationDrugModalityDoseRoute
Comparator Bendamustine Small molecule Intravenous
Subject Duvelisib Small molecule Oral
Comparator Gemcitabine Small molecule Intravenous

Indications