drugset / Trial / NCT06526793

Surovatamig (AZD0486) as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

NCT06526793

Phase 2 Recruiting 270 enrolled AstraZeneca
Non-randomizedSequentialOpen-labelTreatment

Summary

This is a Phase 2 global, multi-center, open-label study to assess the efficacy, safety and tolerability of surovatamig (AZD0486) monotherapy in adult participants with relapsed/refractory B-cell non-Hodgkin lymphoma (NHL) who have received at least two prior lines of therapies. The study has 2 Modules: Module 1 for FL and Module 2 for LBCL.

Timeline

Start
2024-11-27
Primary completion
2027-11-24
Completion
2032-10-21

Drugs

EvaluationDrugModalityDoseRoute
Subject Surovatamig Protein / enzyme biologic Intravenous