drugset / Trial / NCT06528301

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

NCT06528301

Phase 1 Recruiting 106 enrolled Umoja Biopharma
Non-randomizedSequentialOpen-labelTreatment

Summary

This study is a Phase 1 dose-escalation and dose-confirmation study to evaluate the safety and antitumor activity of UB-VV111. The study will enroll patients with relapsed/refractory large B-cell lymphoma (LBCL) and chronic lymphocytic leukemia (CLL).

Timeline

Start
2025-03-10
Primary completion
2029-03
Completion
2029-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Sirolimus Small molecule
Subject UB-VV111 Unknown