drugset / Trial / NCT06538649

Effect of Statins on Crohn's Disease

NCT06538649

Phase 0 Recruiting 20 enrolled Stanford University
RandomizedParallel-groupDouble-blindPrevention

Summary

The goal of this clinical trial is to learn if statins work to prevent strictures in adults with Crohn's disease. The main question it aims to answer is: * Can statins reduce the formation of strictures in participants with stricturing Crohn's disease? Researchers will compare statins to a placebo (a look-a-like substance that contains no drug) to see if statins work to prevent strictures from forming. Participants will: * Take statins or a placebo every day for 6-12 months * Visit the clinic for lab tests twice after starting either statins or placebo * Complete questionnaires about symptoms and medications * Respond to monthly check-ins (via phone call) during participation

Timeline

Start
2024-12-12
Primary completion
2027-10-31
Completion
2028-10-31

Drugs

EvaluationDrugModalityDoseRoute
Subject Rosuvastatin Small molecule 20 mg

Indications